The effect of IMEDEEN can be measured and evaluated by ultrasound skin scanning. Ultrasound is used to determine the condition of the skin’s deeper layer, the dermis.

An image of the skin will be generated that looks like this:

Skin ultrasound
  • The uppermost line in the image depicts the outer layer of the skin (the epidermis). The denser this line appears, the better the functioning of the skin barrier
  • Below the epidermis lies the dermis, the “supporting” layer of the skin. This should appear on the screen as a colored pattern that indicates the amount of collagen, elastin, and moisture retaining elements in the dermis. The deeper the overall color, the denser the concentration of protein fibers in the skin, and, therefore, the better the skin’s condition
  • White areas indicate skin damage
    In other words, dark colors indicate that the skin in good condition. A scan showing more distributed colored areas indicates a better skin quality.
...dark colors indicate that the skin is in good condition. A scan showing more distributed colored areas indicates a better skin quality.

The following ultrasound pictures are taken from a year-long dermatological study of IMEDEEN usage showing the improvements after 3 months, 6 months, and 12 months

Skin at day 0
0 Days
Skin improvements after 3 months
3 Months
Skin improvements after 6 months
6 Months
Skin improvements after 12 months
12 Months
Over time, IMEDEEN can help visibly reduce the appearance of fine lines and wrinkles, dilated capillaries, and age spots while improving the skin’s overall quality and moisture balance.*

On the first scan, the surface of the skin is uneven, indicating inadequate barrier functioning. It is clear that there is an irregular pattern of collagen, elastin, and moisture retaining elements. The white areas show UV or environmental damage, indicating skin that is likely to age prematurely.

By month 3, you can see improvements to both the epidermis (the skin you see) and the dermal layer.

On the final scan, after 12 months’ use of IMEDEEN, the image contains a much more even pattern of dark colors, which represent the essential collagen, elastin, and moisture retaining elements. The result is softer, smoother, more supple skin with an improved barrier function.

Over time, IMEDEEN can help visibly reduce the appearance of fine lines and wrinkles, dilated capillaries, and age spots while improving the skin’s overall quality and moisture balance.*

The study was carried out by the Danish dermatologist Dr Marianne Kieffer. She performed a year-long clinical study on the effects of IMEDEEN on 144 women, aged 35-50 years, all of whom had mild to moderate signs of skin aging. At the end of the study, a statistically significant improvement was shown in all the objective measuring tests. This led Dr Kieffer to conclude that IMEDEEN is active in the dermis, where it improves basic skin structure and texture and the skin’s natural ability to retain moisture, as opposed to moisturizing creams and lotions that work only on the skin’s surface.

Download IMEDEEN Published Studies PDF >